Cobalt is a component of cynocobalamin (vitamin B12), which is an essential mineral and coenzymes in many enzymatic reactions, including hematopoiesis.
No function of cobalt in human nutrition other than as an integral part of vitamin B12. The vitamin plays important role in the body, especially in cells where active division is taking place, such as in blood forming tissues of bone marrow.
The main target organs for cobalt toxicity appear to be lungs and heart.
Acute toxicity of cobalt nay be observed as effects on the lungs, including asthma pneumonia and wheezing, that have been found in workers who breathed high levels of cobalt in the air and exposed to its dust and fumes.
Cobalt can erythropoietic when excessive amounts are ingested by humans. Chronic oral administration of high levels of cobalt for the treatment of anemia can cause goiter.
Cobalt toxicity is classically identified with several instances of severe cardiac failure in heavy beer drinkers. In addition who drink large amounts of beer, containing 1-2 ppm of cobalt salts added as a foam stabilizer, in many cases polycythemia, pericardial effusion, thyroid epithelia hyperplasia and neurological abnormalities.
Health Effects of Cobalt Toxicity
The Most Popular Post
-
Catechins may also be called flavan-3-ols, which represent a relatively small group of the flavonoid class of natural products, while proant... -
In spite of the numerous ways by which the appearance attributes of food affect consumer acceptance, the majority of research on the role of... -
The hydrogenation process in food production involves chemically adding hydrogen to unsaturated fatty acids found in oils and fats. This rea... -
The human body contains approximately 1.3 g of sodium. About a third is found in our bones. The rest is our body fluids. It ensures a proper...
-
Cobalt is a component of cynocobalamin (vitamin B12), which is an essential mineral and coenzymes in many enzymatic reactions, including hem...